Synthesis of Novel Fused Pyrimidines and Imidazoles as Potential Analgesics from 2-Amino-4-substituted-s-triazino[1,2-a]-benzimidazoles
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چکیده
منابع مشابه
Synthesis of Novel Fused Pyrimidines and Imidazoles as Potential Analgesics from 2-Amino-4-substituted-s- triazino[1,2-a]-benzimidazoles
The synthesis of novel fused pyrimidines and imidazole derivatives from 2-amino-s-triazino[1,2a]benzimidazoles 2a-e and 3a-c was successfully carried out by a ring annelation reaction in a very good yield. Compound 3c was screened for analgesic activity against acetic acid irritation and has shown protection equal to the reference drug (diclofenac sodium). The acute toxicity study revealed that...
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ژورنال
عنوان ژورنال: Oriental Journal of Chemistry
سال: 2015
ISSN: 0970-020X,2231-5039
DOI: 10.13005/ojc/310213